NCI Dictionary of Cancer Terms
The NCI Dictionary of Cancer Terms features 8,389 terms related to cancer and medicine.
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A rare, inherited disorder that is caused by mutations (changes) in the TP53 gene. Having Li-Fraumeni syndrome increases the risk of developing many types of cancer. Cancers often develop at an early age, and more than one type of cancer may occur in the same person. LFS is a type of hereditary cancer syndrome. Also called Li-Fraumeni syndrome.