NCI Dictionary of Cancer Terms

The NCI Dictionary of Cancer Terms features 8,467 terms related to cancer and medicine.

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A drug used to treat non-small cell lung cancer that has spread to other parts of the body and is anaplastic lymphoma kinase (ALK) positive. It is used in patients whose cancer got worse during treatment with crizotinib (a type of anticancer drug) and at least one other ALK inhibitor or during treatment with alectinib or ceritinib (other ALK inhibitors). It is also being studied in the treatment of other types of cancer. Lorbrena blocks certain proteins made by the ALK gene. Blocking these proteins may stop the growth and spread of cancer cells. Lorbrena is a type of tyrosine kinase inhibitor. Also called lorlatinib.