NCI Dictionary of Cancer Terms

The NCI Dictionary of Cancer Terms features 8,573 terms related to cancer and medicine.

We offer a widget that you can add to your website to let users look up cancer-related terms. Get NCI’s Dictionary of Cancer Terms Widget.

androgen receptor blocker
(AN-droh-jen reh-SEP-ter BLAH-ker)
A substance that keeps androgens (male sex hormones) from binding to proteins called androgen receptors, which are found in normal prostate cells, some prostate cancer cells, and in cells of some other tissues. Preventing this binding blocks the effects of these hormones in the body. Treatment with androgen receptor blockers may keep prostate cancer cells from growing. Examples of androgen receptor blockers used to treat prostate cancer are apalutamide, bicalutamide, enzalutamide, flutamide, and nilutamide. Also called androgen receptor antagonist and antiandrogen.