NCI Dictionary of Cancer Terms

The NCI Dictionary of Cancer Terms features 8,531 terms related to cancer and medicine.

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selinexor
(SEH-lih-NEK-sor)
A drug used with dexamethasone to treat adults with multiple myeloma that has come back or has not gotten better after treatment with at least four other anticancer therapies that included at least two proteasome inhibitors, at least two immunomodulating agents, and an anti-CD38 monoclonal antibody. It is also being studied in the treatment of other types of cancer. Selinexor blocks a protein called CRM1, which may help keep cancer cells from growing and may kill them. It is a type of small molecule inhibitor. Also called Xpovio.