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atypical squamous cells, cannot exclude a high-grade lesion

(ay-TIH-pih-kul SKWAY-mus sels, KA-not ek-SKLOOD … hy-grayd LEE-zhun)
A finding of abnormal cells in a Pap test. It means there are abnormal squamous cells in the tissue that lines the outer part of the cervix. Atypical squamous cells, cannot exclude a high-grade lesion may be a sign of a high-grade squamous intraepithelial lesion (HSIL), which may become cervical cancer if untreated. More testing may be needed. Also called ASC-H.
Search NCI's Dictionary of Cancer Terms