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cold knife cone biopsy

(kold nife kone BY-op-see)
A procedure in which a cone-shaped piece of abnormal tissue is removed from the cervix using a scalpel or laser knife. Some of the tissue is then checked under a microscope for signs of disease, such as cervical cancer. Cold knife cone biopsy may also be used to treat certain cervical conditions. Also called cold knife conization.
Search NCI's Dictionary of Cancer Terms