CYLD gene
(… jeen)
A gene that makes a protein involved in controlling cell growth, cell division, and a type of cell death called apoptosis. Mutations (changes) in the CYLD gene may cause cells to grow and divide too quickly or in an uncontrolled way. This may cause abnormal cells, including cancer cells, to grow. CYLD gene mutations have been found in an inherited condition called Brooke-Spiegler syndrome and in some types of cancer, including multiple myeloma and cancers of the kidney, liver, uterus, and colon. The CYLD gene is a type of tumor suppressor gene.