DNA repair disorder
(… reh-PAYR dis-OR-der)
A type of inherited disorder caused by mutations (changes) in certain genes involved in DNA repair. Changes in these genes can cause breaks, rearrangements, and other problems in the DNA. There are many different types of DNA repair disorders. Most of these disorders are marked by growth and developmental problems, premature aging, and disorders of the skin and nervous system. Having a DNA repair disorder may increase a person’s risk of certain types of cancer. Also called DNA repair deficiency syndrome.