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Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted.

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Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

dose-dependent

(dose-deh-PEN-dent)
Refers to the effects of treatment with a drug. If the effects change when the dose of the drug is changed, the effects are said to be dose-dependent.
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