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double-hit lymphoma

(DUH-bul-hit lim-FOH-muh)
A rare, aggressive (fast-growing) type of B-cell non-Hodgkin lymphoma caused by changes in the DNA that affect a gene called the MYC gene and either the BCL2 gene or the BCL6 gene. Double-hit lymphoma may be hard to treat and has a poor prognosis. It is a type of diffuse large B-cell lymphoma. Also called DHL.
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