glucarpidase
(gloo-KAR-pih-dayz)
A drug used to treat toxic levels of the anticancer drug methotrexate in the blood of adults and children with kidney problems. Glucarpidase is a bacterial enzyme that helps break down and remove methotrexate from the body. It may also help certain drugs kill cancer cells. Glucarpidase is a type of chemoprotective agent and a type of prodrug activator. Also called carboxypeptidase-G2 and Voraxaze.