histrelin acetate

A drug used under the brand name Vantas as palliative therapy for advanced prostate cancer. Histrelin acetate initially causes the pituitary gland to make more luteinizing hormone (LH) and follicle-stimulating hormone (FSH), temporarily increasing testosterone levels in men. With continued use, histrelin acetate lowers the amount of LH and FSH the pituitary gland releases, leading to a drop in testosterone levels. Histrelin acetate is also used under the brand name Supprelin LA to treat early puberty in males and females. It is a type of hormone therapy called a luteinizing hormone-releasing hormone (LHRH) agonist and a type of androgen deprivation therapy that is reversible.