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hot tumor

(hot TOO-mer)
Describes a tumor that is likely to trigger a strong immune response. Hot tumors often have many molecules on their surface that allow T cells (a type of immune cell) to attack and kill the tumor cells. Hot tumors usually respond to immunotherapy. Melanoma, non-small cell lung cancer, and cancers of the bladder, head and neck, kidney, and liver are usually considered hot tumors.
Search NCI's Dictionary of Cancer Terms