NCI Dictionary of Cancer Terms

The NCI Dictionary of Cancer Terms features 8,643 terms related to cancer and medicine.

We offer a widget that you can add to your website to let users look up cancer-related terms. Get NCI’s Dictionary of Cancer Terms Widget.

A drug used to treat acute myeloid leukemia (AML) that has recurred (come back) or has not gotten better after treatment with other anticancer therapy. It is used in patients whose cancer has a mutated (changed) form of a gene called isocitrate dehydrogenase-2 (IDH2). It is also being studied in the treatment of other types of cancer. Idhifa blocks the protein made by the mutated IDH2 gene. Blocking this protein may help keep cancer cells from growing. Idhifa is a type of enzyme inhibitor and a type of targeted therapy. Also called enasidenib mesylate.