intrapericardial chemotherapy
(IN-truh-PAYR-ih-KAR-dee-ul KEE-moh-THAYR-uh-pee)
A type of treatment in which anticancer drugs are injected through a thin tube directly into the pericardium (the sac around the heart). Intrapericardial chemotherapy may be used to treat a condition called malignant pericardial effusion, in which fluid collects in the pericardium. It is most often caused by lung cancer, breast cancer, melanoma, leukemia, and lymphoma.