Skip to main content
An official website of the United States government
Español
Government Funding Lapse
Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted.

The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov.

Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

loncastuximab tesirine

(LON-kas-TUK-sih-mab TEH-sih-reen)
A drug used to treat adults with certain types of B-cell non-Hodgkin lymphoma that relapsed (came back) or did not get better after treatment with at least two other types of systemic therapy. It is also being studied in the treatment of other types of cancer. Loncastuximab tesirine contains a monoclonal antibody that binds to a protein called CD19, which is found on some lymphoma cells. It also contains an anticancer drug, which may help kill cancer cells. Loncastuximab tesirine is a type of antibody-drug conjugate. Also called Zynlonta.
Search NCI's Dictionary of Cancer Terms