NAE inhibitor
(… in-HIH-bih-ter)
A substance that blocks an enzyme called NEDD8-activating enzyme (NAE). NAE is involved in important cell functions, such as cell division. Blocking NAE may help keep cancer cells from growing and may kill them. Some NAE inhibitors are being studied in the treatment of cancer. They are a type of targeted therapy. Also called NEDD8-activating enzyme inhibitor.