Skip to main content
An official website of the United States government
Español
Government Funding Lapse
Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted.

The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov.

Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

primary ovarian insufficiency

(PRY-mayr-ee oh-VAYR-ee-un IN-suh-FIH-shen-see)
A condition in which the ovaries stop working and menstrual periods stop before age 40. This can cause fertility problems and symptoms of menopause. Primary ovarian insufficiency means the ovaries do not function normally. This may be because they have been removed by surgery, or it may be caused by some cancer treatments and certain diseases or genetic conditions. Some women with primary ovarian insufficiency sometimes have menstrual periods and may be able to have children. Also called premature ovarian failure.
Search NCI's Dictionary of Cancer Terms