stage II bladder cancerListen to pronunciation(... BLA-der KAN-ser)Cancer has spread through the connective tissue into the muscle layers of the bladder. Stage II bladder cancer may also be described as muscle-invasive bladder cancer.More InformationBladder Cancer StagesEnlarge this image in new windowStage II bladder cancer (muscle-invasive bladder cancer). Cancer has spread through the connective tissue into the muscle layers of the bladder. Search NCI's Dictionary of Cancer TermsStarts withContainsBrowse:ABCDEFGHIJKLMNOPQRSTUVWXYZ#