Supprelin LA
(suh-PREH-lin ...)
A drug used to treat early puberty in males and females. Supprelin LA initially causes the pituitary gland to make more luteinizing hormone (LH) and follicle-stimulating hormone (FSH), temporarily increasing testosterone levels in males and estrogen levels in females. With continued use, Supprelin LA lowers the amount of LH and FSH the pituitary gland releases, leading to a drop in testosterone levels in males and estrogen levels in females. Supprelin LA contains the active ingredient histrelin acetate. It is a type of hormone therapy called a luteinizing hormone-releasing hormone (LHRH) agonist and a type of androgen deprivation therapy that is reversible.