tyrosinemia
(TY-roh-sih-NEE-mee-uh)
A rare, inherited disorder marked by high blood levels of a protein building block called tyrosine. This can cause a harmful buildup of tyrosine and other substances in the body’s tissues and organs, especially in the liver, kidney, and nervous system. This can lead to serious medical problems and may increase the risk of liver cancer. Tyrosinemia is caused by mutations (changes) in certain genes that make enzymes needed to break down tyrosine.