varicose veinListen to pronunciation(VAYR-ih-kose vayn)A condition in which a vein, most often in the legs, becomes permanently enlarged, twisted, and painful. This may be caused by valves in the vein that don’t work properly or by weakness in the vein walls.Search NCI's Dictionary of Cancer TermsStarts withContainsBrowse:ABCDEFGHIJKLMNOPQRSTUVWXYZ#