NCI Dictionary of Cancer Terms

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The NCI Dictionary of Cancer Terms features 8,176 terms related to cancer and medicine.

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OSI-774
A drug used to treat certain types of non-small cell lung cancer. It is also used with gemcitabine hydrochloride to treat pancreatic cancer that cannot be removed by surgery or has spread to other parts of the body. It is being studied in the treatment of other types of cancer. OSI-774 blocks a protein called epidermal growth factor receptor (EGFR), which may help keep cancer cells from growing. It is a type of EGFR tyrosine kinase inhibitor. Also called CP-358,774, erlotinib hydrochloride, and Tarceva.