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NCI Dictionary of Cancer Terms

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The NCI Dictionary of Cancer Terms features 8,214 terms related to cancer and medicine.

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BRAF (V600E) mutation
(… myoo-TAY-shun)
A specific mutation (change) in the BRAF gene, which makes a protein that is involved in sending signals in cells and in cell growth. This BRAF gene mutation may be found in some types of cancer, including melanoma and colorectal cancer. It may increase the growth and spread of cancer cells. Checking for this BRAF mutation in tumor tissue may help to plan cancer treatment.