NCI Dictionary of Cancer Terms
The NCI Dictionary of Cancer Terms features 8,214 terms related to cancer and medicine.
We offer a widget that you can add to your website to let users look up cancer-related terms. Get NCI’s Dictionary of Cancer Terms Widget.
- dihydrofolate reductase inhibitor
- listen (dy-HY-droh-FOH-layt ree-DUK-tays in-HIH-bih-ter)
- A substance that can build up in cancer cells and block them from using folate. Folate is a nutrient that rapidly dividing cells need to make DNA. Blocking folate use helps keep cancer cells from growing and may kill them. Some dihydrofolate reductase inhibitors are used to treat cancer. A dihydrofolate reductase inhibitor is a type of antifolate. Also called DHFR inhibitor.