NCI Dictionary of Cancer Terms
The NCI Dictionary of Cancer Terms features 8,051 terms related to cancer and medicine.
- DHFR inhibitor
- listen (… in-HIH-bih-ter)
- A substance that can build up in cancer cells and block them from using folate. Folate is a nutrient that rapidly dividing cells need to make DNA. Blocking folate use helps keep cancer cells from growing and may kill them. Some DHFR inhibitors are used to treat cancer. A DHFR inhibitor is a type of antifolate. Also called dihydrofolate reductase inhibitor.