NCI Dictionary of Cancer Terms

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The NCI Dictionary of Cancer Terms features 8,176 terms related to cancer and medicine.

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ibrutinib
(i-BROO-tih-nib)
A drug used to treat chronic lymphocytic leukemia, small lymphocytic lymphoma, and Waldenstrom macroglobulinemia (a type of non-Hodgkin lymphoma). It is also used to treat mantle cell lymphoma and marginal zone lymphoma in patients who have received at least one other treatment. It is also being studied in the treatment of other types of cancer. Ibrutinib blocks a protein called Bruton’s tyrosine kinase (BTK), which may help keep cancer cells from growing. It is a type of tyrosine kinase inhibitor. Also called Imbruvica.