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Technology - Cancer Currents Blog

News and commentaries on technology used to conduct cancer research, deliver cancer treatment, improve patient care, and screen for cancer, as well as other topics.

  • Two tubes of blood with zoom-ins showing DNA fragments.
    • By Nadia Jaber

    Researchers have developed a blood test that, in a preliminary study, accurately detected liver cancer, including in people with early-stage disease. The test uses a new type of technology called fragmentomics to analyze bits of DNA in the blood.

  • A scanning electron micrograph showing chromosomes and ecDNA
    • By Carmen Phillips

    A new study shows for the first time that a circular form of DNA, called ecDNA, is present in precancerous tissue and not just cancer cells. The study also suggested that when ecDNA is present in Barrett’s esophagus, that tissue is almost certain to become cancer.

  • A syringe withdrawing liquid from a glass vial
    • By Edward Winstead

    A new study has compared three formulations of an mRNA vaccine designed to treat cancers caused by human papillomavirus (HPV) infections. All three vaccines showed promise in mice.

  • A young girl with her arm out and gloved hands cleaning a spot on her arm with a swab.
    • By Elia Ben-Ari

    Results from a new study highlight the progress being made toward developing liquid biopsies specifically for use in children with solid cancers like Ewing sarcoma and Wilms tumor. The tests can help detect and diagnose cancer and monitor for response to treatment and recurrence.

  • Woman wearing a head scarf holding a bottle of medication in one hand and looking at her phone in the other hand.
    • By Edward Winstead

    Since the start of the COVID-19 pandemic, many people with cancer have had telehealth visits with their doctors. According to an analysis of nearly 25,500 telemedicine visits to the Moffitt Cancer Center by more than 11,600 adults with cancer, the use of telehealth saved people with cancer time, travel, and money.

  • Illustrations of two next-generation CAR T cells
    • By Sharon Reynolds

    Two research teams have developed ways of overcoming barriers that have limited the effectiveness of CAR T-cell therapies, including engineering ways to potentially make them effective against solid tumors like pancreatic cancer and melanoma.

  • Microscopic image of a dense cluster of human prostate cells in vibrant reds, green and blues.
    • By Nadia Jaber

    The Decipher genomic test found high-risk prostate cancer even when conventional tests said the tumors were lower risk. This discrepancy appeared to happen more frequently for African-American men.

  • Immunofluorescence images of micro-organospheres created from a human lung tumor.
    • By Carmen Phillips

    A research team hopes to offer oncologists a new tool to guide treatment choices for their patients. In a small study, a tumor model called micro-organospheres accurately predicted whether patients would respond to their chemotherapy treatment.

  • Illustration depicting biomarkers in the bloodstream related to a tumor. The cross-section of a blood vessel shows various elements, including red blood cells, protein biomarkers, and circulating free DNA (cfDNA) biomarkers. An arrow points from a cluster of tumor cells into the blood vessel. Another arrow highlights cfDNA biomarkers with a label "Me," indicating methylation.
    • By Philip Castle, Ph.D., M.P.H.

    Progress has been made on developing noninvasive tests that may be able to find many cancers early. But, as NCI’s Dr. Phil Castle explains, there’s still much to learn about these multi-cancer early detection tests before they become widely used.

  • An illustration of IL-2 and IL-15 binding to cell surface receptors.
    • By Elia Ben-Ari

    Researchers have developed tiny “drug factories” that produce an immune-boosting molecule and can be implanted near tumors. The pinhead-sized beads eliminated tumors in mice with ovarian and colorectal cancer and will soon be tested in human studies.

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