Biology of Cancer - Cancer Currents Blog
Cancer biology research news, with context from experts at NCI and elsewhere. Topics include cancer metastasis, the tumor microenvironment, and new targets for cancer therapies.
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Cancer cells may exploit a normal function of neutrophils, the most common form of white blood cell, to help form metastatic tumors, a new study suggests.
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Findings from a new study from NCI researchers could help predict whether a tumor will respond to a new class of promising cancer drugs, and identifies a potential way to overcome that resistance.
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A new study has identified a potentially critical vulnerability in lung cancers that have mutations in the KRAS gene, and showed that a drug already under study may be able to exploit it.
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Studies in cells and mice found that, in cells with damaged DNA, a noncoding RNA called DINO stabilizes the p53 protein and guides the cells into cell death, preventing tumor development.
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Researchers have found that cancer cells can use the compound lactate to fuel biochemical reactions and to generate other compounds they need for growth and survival.
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Two new studies suggest that a new class of drugs can effectively target a molecular driver of the most common type of kidney cancer.
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A new study suggests that a chromosomal instability score may help guide treatment choices for patients with cancer.
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Pancreatic cancer cells instruct healthy cells around them to provide nutrients they need to survive and grow, a new study suggests.
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Stem cells engineered to mimic medulloblastoma development may help researchers identify potential new treatments, according to a new study.
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Researchers identified mutations in relapsed melanoma tumors that block the anticancer effects of the checkpoint inhibitor pembrolizumab.