NCI Dictionary of Cancer Terms

The NCI Dictionary of Cancer Terms features 8,379 terms related to cancer and medicine.

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Gamifant
(GA-mih-fant)
A drug used to treat a rare immune system disorder called primary hemophagocytic lymphohistiocytosis (HLH) that came back, got worse, or did not get better with other therapy. It is also used in patients who cannot be treated with other therapy. Gamifant binds to an immune system protein called interferon gamma, which is found at higher than normal levels in patients with HLH. This may help lower the body’s immune response and reduce inflammation. Gamifant is a type of monoclonal antibody. Also called emapalumab.