Aucatzyl
(aw-KAT-zil)
A drug used to treat adults with acute lymphoblastic leukemia that came back or did not get better during or after other treatment. It is also being studied in the treatment of other conditions and types of cancer. Aucatzyl is made using a patient’s T cells (a type of immune system cell). A gene for a special receptor called chimeric antigen receptor (CAR) is added to the T cells in the laboratory. These changed T cells called CAR T cells are grown in large numbers in the laboratory and given to the patient by infusion. Aucatzyl binds to a protein called CD19, which is found on some leukemia cells. This helps the body’s immune system kill cancer cells. Aucatzyl is a type of CAR T-cell therapy. Also called obecabtagene autoleucel.