Skip to main content
An official website of the United States government
Español
Government Funding Lapse
Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted.

The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov.

Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

DKC1 gene

(... jeen)
A gene that makes a protein involved in protecting and maintaining telomeres (the ends of chromosomes) and in making a molecule called ribosomal RNA. Mutations (changes) in the DKC1 gene may cause damage to chromosomes and DNA, which may lead to abnormal cell growth. DKC1 gene mutations have been found in a rare, inherited condition called dyskeratosis congenita, which causes abnormal changes in the skin and nails and white patches inside the mouth. People with this condition have an increased risk of bone marrow failure (a condition in which the bone marrow does not make enough blood cells), myelodysplastic syndrome, pulmonary fibrosis (scarring of the lungs), and certain types of cancer.
Search NCI's Dictionary of Cancer Terms