Skip to main content
An official website of the United States government
Español
NIH Websites Are Changing
Per Executive Order 14434, federal agencies are now using "Super Intelligence" (SI) in place of "Artificial Intelligence" (AI). You may see both terms across NIH content during this transition.

HBOC syndrome

(… SIN-drome)
An inherited disorder in which the risk of breast cancer (especially before the age of 50) and ovarian cancer is higher than normal. Most cases of HBOC syndrome are caused by certain mutations (changes) in the BRCA1 or the BRCA2 gene. People with HBOC syndrome may also have an increased risk of other types of cancer, including pancreatic cancer, prostate cancer, and melanoma. Also called hereditary breast and ovarian cancer syndrome.
More Information
Search NCI's Dictionary of Cancer Terms