hereditary leiomyomatosis and renal cell cancer

A rare, inherited disorder in which benign (not cancer) skin lesions called leiomyomas form in the smooth muscle tissue around the hair follicles. They usually form on the arms, legs, chest, and abdomen. Benign leiomyomas may also form as fibroids in the uterus in females. People with hereditary leiomyomatosis and renal cell cancer have an increased risk of kidney cancer. The signs and symptoms of hereditary leiomyomatosis and renal cell cancer usually do not appear until young adulthood. Hereditary leiomyomatosis and renal cell cancer is caused by a mutation in the FH gene. It is inherited in an autosomal dominant manner. Also called HLRCC.