Skip to main content
An official website of the United States government
Español
Government Funding Lapse
Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted.

The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov.

Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

hereditary leiomyomatosis and renal cell cancer

(heh-REH-dih-tayr-ee LY-oh-MY-oh-muh-TOH-sis ... REE-nul sel KAN-ser)
A rare, inherited disorder in which benign (not cancer) skin lesions called leiomyomas form in the smooth muscle tissue around the hair follicles. They usually form on the arms, legs, chest, and abdomen. Benign leiomyomas may also form as fibroids in the uterus in females. People with hereditary leiomyomatosis and renal cell cancer have an increased risk of kidney cancer. The signs and symptoms of hereditary leiomyomatosis and renal cell cancer usually do not appear until young adulthood. Hereditary leiomyomatosis and renal cell cancer is caused by a mutation in the FH gene. It is inherited in an autosomal dominant manner. Also called HLRCC.
More Information
Drawing showing areas of the body affected by hereditary leiomyomatosis and renal cell cancer, including the skin, kidneys, and uterus.Enlarge this image in new window
Areas of the body affected by hereditary leiomyomatosis and renal cell cancer (HLRCC). HLRCC is an inherited disorder that causes an increased risk of kidney cancer. It can also cause lesions in the skin and uterus (in females).
Search NCI's Dictionary of Cancer Terms