Hodgkin disease
(HOJ-kin dih-ZEEZ)
A cancer of the immune system that is marked by the presence of a type of cell called the Reed-Sternberg cell. The two major types of Hodgkin disease are classic Hodgkin lymphoma and nodular lymphocyte-predominant Hodgkin lymphoma. Signs and symptoms include painless, swollen lymph nodes, an enlarged spleen, fever, weight loss, fatigue, and night sweats. Also called Hodgkin lymphoma.
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Enlarge this image in new windowReed-Sternberg cell. Reed-Sternberg cells are large, abnormal lymphocytes (a type of white blood cell) that may contain more than one nucleus. These cells are found in people with Hodgkin lymphoma. Reed-Sternberg cells are also called Hodgkin and Reed-Sternberg cells.