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HPRC

A rare, inherited disorder that increases the risk of a type of kidney cancer called type 1 papillary kidney cancer. This cancer forms in cells that line the small tubes in the kidney that filter waste from the blood and make urine. HPRC often affects both kidneys, and often there is more than one tumor in each kidney. It is caused by mutations (changes) in a gene called MET. HPRC is a type of hereditary cancer syndrome. Also called hereditary papillary renal cancer and hereditary papillary renal carcinoma.
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Papillary renal cancer; drawing showing the left kidney, renal pelvis, and ureter. Also shown is a pullout of the renal tubules, which is where urine is made.Enlarge this image in new window
Papillary renal cancer forms in cells that line the renal tubules in the kidney. The renal tubules remove waste from the blood and make urine. Urine moves through the renal tubules into the renal pelvis and ureter, which carries urine from the kidney to the bladder.
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