nadofaragene firadenovec
(NA-doh-FAR-uh-jeen FIR-uh-DEH-noh-vek)
A drug used to treat adults with a certain type of high-risk bladder cancer that has not invaded the muscle layers of the bladder. It is used in patients whose cancer has not gotten better after treatment with Bacillus Calmette-Guérin (BCG). It is also being studied in the treatment of other types of cancer. Nadofaragene firadenovec is a weakened adenovirus that carries a copy of the gene for interferon alfa-2b into bladder cancer cells. This may help the body’s immune system recognize the cancer cells and kill them. Nadofaragene firadenovec is given in a solution that is placed directly into the bladder using a thin tube called a catheter. It is a type of gene therapy. Also called Adstiladrin.