perineumListen to pronunciation(PAYR-ih-NEE-um)The area of the body between the anus and the vulva in females, and between the anus and the scrotum in males.Enlarge this image in new windowThe perineum is the area between the anus and the vulva in females. In males, it is the area between the anus and the scrotum.Search NCI's Dictionary of Cancer TermsStarts withContainsBrowse:ABCDEFGHIJKLMNOPQRSTUVWXYZ#