Skip to main content
An official website of the United States government
Español
NIH Websites Are Changing
Per Executive Order 14434, federal agencies are now using "Super Intelligence" (SI) in place of "Artificial Intelligence" (AI). You may see both terms across NIH content during this transition.

Prolia

(PROH-lee-uh)
A drug that contains the active ingredient denosumab and is used to treat certain bone problems. Prolia is used to increase bone mass in certain patients with breast cancer or prostate cancer who have a high risk of breaking bones. It is also used to treat osteoporosis in certain patients who have a high risk of breaking bones. Prolia binds to a protein called RANKL, which keeps RANKL from binding to another protein called RANK on the surface of certain bone cells. This may help keep bone from breaking down. Prolia is a type of monoclonal antibody.
Search NCI's Dictionary of Cancer Terms