sentinel lymph nodeListen to pronunciation(SEN-tih-nul limf node)The first lymph node to which cancer is likely to spread from the primary tumor. When cancer spreads, the cancer cells may appear first in the sentinel node before spreading to other lymph nodes.More InformationSentinel Lymph Node BiopsySearch NCI's Dictionary of Cancer TermsStarts withContainsBrowse:ABCDEFGHIJKLMNOPQRSTUVWXYZ#