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Radiation Proctitis

What is radiation proctitis?

Radiation proctitis can happen when radiation therapy damages the lining of the rectum. Radiation proctitis causes diarrhea and other digestive issues and is most common in people who receive radiation therapy aimed at the rectum and sigmoid colon (lower part of the colon). Radiation therapy for rectal, prostate, and cervical cancers is most likely to cause radiation proctitis.

Radiation proctitis can be acute or chronic. Acute radiation proctitis begins shortly after you start radiation treatment and goes away a few weeks after radiation treatment ends.

Learn more about chronic radiation proctitis, including its symptoms and how to manage them, in the Digestive System Problems section in Late Effects of Cancer Treatment.

What are signs and symptoms of radiation proctitis?

It’s important to tell your doctor if you notice any of these problems. Signs and symptoms of radiation proctitis include:

Learn about other digestive system problems in people with cancer

  • diarrhea
  • frequent or persistent urges to have a bowel movement
  • abdominal pain or cramps
  • blood or mucus in stool

These symptoms are often more severe if you have chronic radiation proctitis. Chronic radiation proctitis may also cause symptoms such as rectal pain and bleeding and being unable to control your bowel movements.

Symptoms of radiation proctitis may be caused by conditions other than radiation proctitis, so tell your doctor about any digestive problems to get a proper diagnosis and treatment.

Radiation enteritis is a condition with symptoms like those of radiation proctitis, but radiation enteritis is caused by damage to the lining of the intestines. Learn more at Radiation Enteritis.

Risk factors for radiation proctitis

Your risk of developing radiation proctitis may be higher if you:

Talk with your doctor or nurse about steps you can take to lower your risk of developing radiation proctitis. Keep in mind that newer radiation therapy techniques may lower the risk of radiation proctitis in people being treated for cancer. Stereotactic body radiation therapy and intensity-modulated radiation therapy, for example, may help avoid damage to the rectum’s healthy cells during treatment.

How is radiation proctitis diagnosed?

If you have symptoms of radiation proctitis, your doctor will do a physical exam and ask about your symptoms and your current or prior cancer treatments. Your doctor may also use imaging tests such as a sigmoidoscopy, CT scan, or MRI to diagnose radiation proctitis and plan treatment.

You may also need a stool test and blood test to rule out infection or other conditions that may be causing your symptoms.

How is radiation proctitis managed and treated?

If you develop radiation proctitis during or shortly after receiving radiation therapy, your treatment may focus on relieving symptoms. Your doctor may suggest medicines and changes to your diet, such as eating frequent small meals, low-fiber foods, and foods high in sodium or potassium.

Learn about specific food and drink choices that could help you manage diarrhea from radiation proctitis at Diarrhea and Cancer Treatment. You can also find helpful tips on managing symptoms of radiation proctitis at Nutrition During Cancer Treatment and in our booklet Eating Hints: Before, During, and After Cancer Treatment.

Learn more about how chronic radiation proctitis is managed in the Digestive System Problems section in Late Effects of Cancer Treatment.

Talking with your doctor about radiation proctitis

Tell your health care team if you have symptoms of radiation proctitis. They can help you find ways to manage this side effect of cancer treatment.

Questions to ask your provider about radiation proctitis:

  • What symptoms or problems should I call you about?
  • What medicines can I take for diarrhea and other radiation proctitis symptoms?
  • What can help decrease rectal pain and irritation?
  • What liquids and foods should I have each day? What ones should I avoid?
  • Could I meet with a registered dietitian?

Getting support if you have radiation proctitis

Side effects like radiation proctitis can be hard to deal with, both physically and emotionally. It’s important to ask for support from your health care team. They can help you prepare for and make it through difficult times. Learn more about ways to cope with cancer, including ways to adjust to daily life during cancer treatment.

Caring for someone with radiation proctitis

For family members and friends who are caring for someone with cancer, you may find these suggestions for caregivers to be helpful.

Here are some ways to help your loved one:

  • Encourage the person you are caring for to drink water or other fluids their doctor suggests. Provide them with a water bottle they can carry and refill throughout the day.
  • Try to keep the person’s pantry stocked with foods that can help relieve radiation proctitis symptoms. Learn more about these foods at Diarrhea and Cancer Treatment.
  • Encourage the person you are caring for to take warm, shallow baths (sometimes called sitz baths) that can help relieve pain and irritation from diarrhea. 
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