Pediatric Leukemia and Lymphoma Steering Committee

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The Pediatric Leukemia and Lymphoma Steering Committee (PLLSC) was established in 2011. PLLSC members include representatives from the Children's Oncology Group, pediatric and medical oncologists and other specialists, translational scientists, biostatisticians, patient advocates, and NCI staff.

Mission Statement

The PLLSC follows a data-driven, transparent process to identify and promote the "Best Science" in clinical research for pediatric and adolescent patients with leukemia, lymphoma, and other hematologic malignancies by evaluating and prioritizing phase 2 and phase 3 clinical trial concepts.

Roster of Pediatric Leukemia and Lymphoma Steering Committee (PLLSC) members

Remembering Robert J. Arceci, M.D., Ph.D., - PLLSC Vice-Chair (2011-2014) and Chair (2014-2015)

2015 Pediatric Leukemia and Lymphoma Steering Committee Strategic Priorities

PLLSC Activities

Relevant Workshops

  • MRD Working Group – November 2012

Clinical Trials

The following are clinical trials that were approved at the concept stage by the Steering Committee:

Trial ID NCT ID Trial Title
COG-ANHL1131 NCT01516580 Intergroup Randomized Trial for Children or Adolescents with B-cell Non-Hodgkin Lymphoma (NHL) or B-Acute Leukemia (B-AL): Rituximab Evaluation in High Risk Patients
COG-ASCT1221 NCT01824693 A Randomized Phase II Study Comparing Two Different Conditioning Regimens Prior to Allogeneic Hematopoietic Cell Transplantation (HCT) for Children with Juvenile Myeolomonocytic Leukemia (JMML)
COG-ANHL12P1 NCT01979536 A Pilot Study of Brentuximab Vedotin and Crizotinib in Patients with Newly Diagnosed Stage II-IV Anaplastic Large Cell Lymphoma

Find all NCI-sponsored clinical trials.

CCCT Contact: Wolf Lindwasser, Ph.D.