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Cancer Currents: An NCI Cancer Research Blog

A blog featuring news and research updates from the National Cancer Institute.

An illustrated banner to represent NCI's Cancer Currents research news blog. The design features interconnected scenes: a patient receiving care, a researcher in a lab, a tumor model, a laptop and mobile device displaying research articles, fitness activity, a clinical setting, and a researcher giving a scientific presentation. The background showcases rolling hills and abstract buildings.
  • A patient in a hospital gown lies on a treatment table beneath a large linear accelerator machine during a radiation therapy session.
    • By Sharon Reynolds

    Many with prostate cancer can safely receive shorter, higher-dose radiation therapy after surgery, a new study has found. The approach, called HYPORT, didn’t harm patients’ quality of life compared with the standard radiation approach, trial finds.

  • A super resolution image of killer T cells, stained in green and red, surrounding a cancer cell, stained in blue.
    • By Justin Benavidez

    The CAR T-cell therapy Tecartus has become the first such treatment approved by FDA to treat adults with acute lymphoblastic leukemia (ALL). The approval is for patients whose cancer has not responded to treatment or returned after treatment.

  • A protein-protein "interactome" of protein-protein interactions.
    • By Carmen Phillips

    A research team has identified common interactions between cancer-related proteins in cancer cells. They also created a map of how these protein complexes function in those cells and identified a promising treatment target for head and neck cancer.

  • A microscopic cross section of intestinal villi
    • By Sharon Reynolds

    Excess fructose can promote obesity and colorectal cancer, a new study shows. In mice, the study found that the sweetener, a component of table sugar and high-fructose corn syrup, increased how long normal and cancer cells in the intestines live.

  • Illustration of Stage IIIA Lung Cancer (1), showing a cross-section of the lungs. Labeled features include cancer in lymph nodes around the trachea, carina, left main bronchus, and pleura. Part of the lung has collapsed or has pneumonitis. Insets show the primary tumor, which is 5 cm or smaller, compared to a lime for size reference, and a close-up of the membrane covering the lung near the rib.
    • By Edward Winstead

    Atezolizumab (Tecentriq) is now the first immunotherapy approved by FDA for use as an additional, or adjuvant, treatment for some patients with non-small cell lung cancer. The approval was based on results of a clinical trial called IMpower010.

  • A factoid illustrating the 13% to 23% increase in parents safety concerns.
    • By Nadia Jaber

    Despite consistent evidence that HPV vaccines are safe and effective, a new study shows that more parents are citing concerns about their safety. Researchers cautioned that efforts are needed to counter this trend and improve vaccination rates.

  • An illustration of trastuzumab deruxtecan's mechanism of action
    • By Elia Ben-Ari

    In people with metastatic HER2-positive breast cancer, the targeted drug trastuzumab deruxtecan (Enhertu) markedly lengthened progression-free survival compared with trastuzumab emtansine (Kadcycla), new study results show.

  • Bethany ross from the back with a "survivor neuroendocrine cancer" shirt
    • By Edward Winstead

    New treatments are helping more people with advanced or metastatic cancer live longer. At a recent NCI conference, survivors and researchers came together to discuss how to better address the needs of those living with metastatic cancer.

  • Close-up view of a medical procedure being performed on a person’s hand, showing a healthcare provider using surgical tools while another assists with a cotton swab.
    • By Linda Wang

    Trial results show patients who received the immunotherapy pembrolizumab (Keytruda) after surgery to remove high-risk stage II melanomas were less likely to have the cancer come back than those who received no treatment after surgery.

  • graphic of the mode of action of CDK4/6 inhibitors
    • By Carmen Phillips

    In a large clinical trial, women with HR-positive, HER2-negative metastatic breast cancer treated with ribociclib (Kisqali) and letrozole (Femara) as their initial treatment lived approximately 1 year longer than women treated with letrozole only.

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