Leadership & Expert Views - Cancer Currents Blog
Commentaries from scientific leaders at NCI and other institutions about cancer research topics, programs, and initiatives.
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Following ASCO 2026, NCI Director Dr. Anthony Letai reflects on the pace of progress in cancer research, efforts to accelerate clinical trials, and NCI’s role in supporting the cancer research and care community. He highlights how decades of investment in science are driving progress for patients and creating new opportunities to improve outcomes.
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NCI Director Dr. Anthony Letai shares his reflections on this year’s AACR Annual Meeting, including science that stood out and NCI’s leading priorities.
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NCI Director Dr. Kimryn Rathmell reviews some of the most noteworthy cancer research findings from 2024, including advances in immunotherapy for children with cancer, a potential therapy for cachexia, and studies that provided valuable insights into cancer biology.
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NCI Director Dr. Kimryn Rathmell and Division of Cancer Biology Director Dr. Dan Gallahan explain how the R15 grant program supports researchers at smaller institutions and encourages students to pursue careers in cancer research.
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In late 2023, FDA announced it was investigating instances of second cancers following treatment with CAR T-cell therapies. In this Q&A, NCI’s Dr. Stephanie Goff explains what’s known about the issue, stressing that second cancers “of any kind are rare.”
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Drs. Ruth Pfeiffer and Peter Kraft of NCI’s Division of Cancer Epidemiology and Genetics discuss how breast cancer risk assessment tools are created and how people can use them to understand and manage their risk.
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Reshaping the cancer clinical trials infrastructure to overcome key bottlenecks will involve embracing technology and collaboration, and inviting innovation, explain NCI Director Dr. W. Kimryn Rathmell and NCI Special Advisor Dr. Shaalan Beg.
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NCI’s James H. Doroshow, M.D., reflects on the accomplishments of NCI-MATCH, a first-of-its-kind precision medicine cancer trial, and gives an overview of three new successor trials: ComboMATCH, MyeloMATCH, and iMATCH.
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An NIH-led study called IDENTIFY is analyzing what happens when prenatal blood tests in a pregnant person suggests the person may have cancer. Dr. Diana Bianchi and Amy Turriff talk about their experience with the study thus far.
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In this Q&A, NCI Director Dr. Monica Bertagnolli and Deputy Director for Clinical and Translational Research Dr. James Doroshow explain the challenges of cancer clinical trials and important steps NCI is taking to improve their effectiveness.