July 2018 - Cancer Currents Blog
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Aggressive Prostate Cancer Subtype More Common Than ExpectedResearchers have found that men with advanced prostate cancer may be more likely than previously thought to develop a more aggressive form of the disease. The subtype, called t-SCNC, was linked with shorter survival than other subtypes.
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Developing Biomarkers for Immunotherapy: A Conversation with Drs. Magdalena Thurin and Helen ChenNCI is supporting a new research network to develop biomarkers for cancer immunotherapy. In this interview, NCI’s Dr. Helen Chen and Magdalena Thurin explain the networks’ structure and its goals.
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FDA Alters Approved Use of Two Checkpoint Inhibitors for Bladder CancerFDA has changed the approved uses of the immunotherapy drugs pembrolizumab (Keytruda) and atezolizumab (Tecentriq) to treat the most common form of bladder cancer. The change is based on whether patients’ tumors have a specific biomarker.
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Mouse Study Links Immune Cells to Diarrhea Caused by ChemotherapyA study in mice sheds light onto how some chemotherapies cause diarrhea. The findings could be the basis for developing new treatments for patients with cancer who develop gastrointestinal side effects from chemotherapy.
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The Opioid Epidemic and Cancer Pain Management: A Conversation with Dr. Judith PaiceDr. Judith Paice, of the Cancer Pain Program at Northwestern University’s Feinberg School of Medicine, discusses the impacts of the opioid epidemic on cancer patients and how providers can address concerns about opioid misuse when managing cancer pain.
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Sodium Thiosulfate Prevents Cisplatin-Induced Hearing Loss in Some ChildrenThe drug sodium thiosulfate can protect the hearing of children with cancer undergoing treatment with the chemotherapy drug cisplatin, results from a new clinical trial show. The trial involved children with a form of liver cancer called hepatoblastoma.
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Cancer Prevention Message Is Key for HPV Vaccination Discussions with ParentsHealth care providers should emphasize cancer prevention when discussing HPV vaccination with the parents of preteens who are due to receive the vaccine, results from a new study show.
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Can Age Affect Response to Immune Checkpoint Inhibitors?A new study has linked age with how well patients with melanoma responded to treatment with immune checkpoint inhibitors. Experiments in mice suggested that the response pattern may be due to an age-related shift in the kinds of immune cells in tumors.
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Dr. Alan S. Rabson, Long-Time NCI Deputy Director and Cancer Research Stalwart, DiesMany in the cancer research and NIH community are mourning the loss of long-time NCI senior leader Alan Rabson, M.D., who passed away on July 4, at the age of 92. His career spanned 6 decades, including research on tumor virology and cancer pathology and senior NCI leadership roles.