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NCI Drug Dictionary

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The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

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niacinamide
The active form of vitamin B3 and a component of the coenzyme nicotinamide adenine dinucleotide (NAD). Niacinamide acts as a chemo- and radio-sensitizing agent by enhancing tumor blood flow, thereby reducing tumor hypoxia. This agent also inhibits poly(ADP-ribose) polymerases, enzymes involved in the rejoining of DNA strand breaks induced by radiation or chemotherapy. Check for active clinical trials using this agent. (NCI Thesaurus)

Synonym:3-Pyridinecarboxamide
nicotinamide
Nicotinamidum
Nicotinic Acid Amide
Nicotylamide
Pellagra-Preventing Factor
Vitamin PP
Foreign brand name:Nicamid
Nicosedine